JHS
Coriolus
Coriolus
Couldn't load pickup availability
CORIOLUS SUPER STRENGTH (PROTEIN-BOUNDPOLYSACCHARIDE)
Over 300 studies have been conducted and published on the immune supporting* properties of the 1-4, 1-3, 1-6 linked proteoglycans extracted from the cell walls of Coriolus versicolor, including 24 human clinical studies (14 placebo controlled, double-blind, human clinical trials). With Japanese sales exceeding $350 million annually, the cell-wall extract of Coriolus versicolor has become one of the most widely used supplements in the world for addressing immune health.* Decoctions of Coriolus versicolor have been used for centuries in Traditional Chinese Medicine (TCM), with references in the Chinese Compendium of Materia Medica dating as far back as the 15th century. The Ming dynasty edition states that, “The black and green Yun zhi are beneficial to one’s spirit and vital energy, and strengthen one’s tendon and bone.”
HOW SUPPLIED
- 150 Vcaps
- 500 mg per Vcap
INDICATIONS
Tonic Immune Support,* Immune Challenges,* Hepatic Issues.*
INSTRUCTIONS FOR USE
One to three capsules twice daily, AM and PM, on an empty stomach.
TOXICITY, CAUTIONS, CONTRADICTIONS
Coriolus polysaccharides are safe and non-toxic, having been used daily in clinical studies lasting five to ten years. However, immuno- modulating substances should be avoided completely in organ- transplant patients utilizing immuno- suppressive agents.
CLINICAL RESEARCH
The research shows that the polysaccharide portion of the extract enhances the cell-mediated immune response.* The 1-4, 1-3, 1-6 proteoglycans act as a biological response modifier and have been found to support and enhance Natural Killer cell function, to stimulate depressed lymphocyte proliferation, and to support the healthy growth of white blood cells.* The research also shows these constituents to be effective at supporting normal cell growth, improving cell-mediated cytotoxicity, and increasing interleukin-2 production and T-cell proliferation.*
SELECTED CLINICAL STUDIES
The results of an eight-year human clinical study, published in 1990, recorded substantial benefit from the daily use of the Coriolus 1-4, 1-3, 1-6 extract. The group receiving the Coriolus extract experienced significant improvements in immune health* as compared to the group receiving the placebo, with the leukocyte activity of the Coriolus group showing “remarkable enhance- ment.” It was concluded that “the beneficial effects were probably due to the activation of leukocyte function* as one of the many bio-logical- response-modifying activities induced by (Coriolus).” In a study published in Lancet, Coriolus was found to have a “restorative effect in patients who have been immuno-suppressed.”*
TRADITIONAL USE AND PREPARATION
Coriolus is sweet in taste and slightly warm in nature, acting through the spleen and heart meridians. It dispels damp and reduces phlegm.1In TCM,Coriolus is prepared as hot water extraction/ decoction.2Coriolus is never used in the un-extracted form or prepared as an alcohol tincture.
ACTIVE CONSTITUENTS
Heavy Molecular Weight Polysaccharides (1-4. 1-3. 1-6 linked proteoglycans extracted from cell walls).
EXTRACTION INFORMATION
Hot water extracts from both the fruit body and the mycelium are used in current clinical practice and the published research. The active constituents, the protein-bound polysaccharides, are found inside the cell walls of both, although extracts from the fruit body have shown higher levels of immune activity* with oral use.3Super Strength is isolated using a multi-step hot water extraction process, creating a high concentration of the 1-4, 1-3, 1-6 cell- wall constituents examined in the Japanese research. As these compounds are difficult to extract and easily degraded with excessive heat, NMR and linkage analysis are used to ensure product quality.
REFERENCES
- Hobbs, C., Medicinal Mushrooms, Botanica Press
- Liu, b., Bau, , Fungi Pharmacopeia. Kiniko Press, 1980.
- Hotta, et al., US Patent #4,271,151.1981.
Share
